Position

Burnet Senior Fellow, Burnet Institute
Honourary Senior Lecturer, Monash University

Contact

Research interests

• Modeling diversity-covering malaria vaccines from natural population data
• Population biology and epidemiology of two newly identified malaria species
• Var gene diversity and naturally acquired immunity to malaria
• Population genomics of Plasmodium spp. in Papua New Guinea
• NIH International Centre for Excellence in Malaria Research (Collaborator): Research to Control and Eliminate Malaria in SE Asia and SW Pacific

Qualifications

BSc(Hons) Tas PhD Melb

Ten Most Significant Publications

1. Volkman, S.*, BARRY, A.*, Lyons, E.J., Thomas, S., Nielsen, K., Day, K.P., Wirth, D.F., and Hartl, D. Recent Origin of Plasmodium falciparum from a Single Progenitor. (2001) Science 293(5529): 416-7 *equal contribution
2. Hartl, D.L., Volkman, S.K., Nielsen, K.M., BARRY, A., Day, K.P., Wirth, D.F. and Winzeler,E.A. (2002) The paradoxical population genetics of Plasmodium falciparum. Trends in Parasitology 18(6): 266-272
3. BARRY, A., Leliwa, A., Choi, M., Nielsen, K., Hartl, D., and Day, K.P. (2003) Artifacts in sequence data from the human malaria parasite, Plasmodium falciparum. Molecular and Biochemical Parasitology 130 (2): 143-7
4. BARRY, A.E., Leliwa-Sytek, A., Kasper, J., Hartl, D. and Day K.P. (2006) Variable SNP density in aspartyl protease genes of the malaria parasite Plasmodium falciparum. Gene 376(2):163-73
5. BARRY, A.E., Leliwa-Sytek, A., Tavul, L., Imrie, H., Migot-Nabias, F., Brown, S.M., McVean, G., Day, K.P. (2007) Population genomics of the immune evasion (var) genes of Plasmodium falciparum. PLoS Pathogens 3(3): e34
6. BARRY, A.E., Schultz L, Buckee CO, Reeder JC, (2009) Contrasting Population Structures of the Genes Encoding Ten Leading Vaccine-Candidate Antigens of the Human Malaria Parasite, Plasmodium falciparum. PLoS ONE 4(12): e8497. doi:10.1371/journal.pone.0008497
7. Reiling, L.., Richards, J.S., Fowkes, F.J.I., BARRY, A.E., Triglia, T., Chokejindachai, W., Michon, P., Tavul. L.., Siba, P.M., Cowman, A.F., Mueller, I., Beeson, J.G. (2010) Evidence that the erythrocyte invasion ligand PfRh2 is a target of protective immunity against Plasmodium falciparum malaria J. Immunol. 185(10):6157-67
8. Schultz, L. Wapling, J., Mueller, I., Senn, N., Ntsuke, P.O., Buckee, C.O., Nale, J., Kiniboro, B., Siba, P.M., Reeder, J.C. and BARRY, A.E.. (2010) Multilocus haplotypes reveal variable genetic diversity and population structure in Papua New Guinea, a region of intense perennial transmission. Malaria Journal 9: 336
9. BARRY, A.E.*, Chen, D.*, Smith, T.A., Petersen, I., Migot-Nabias, F., Deloron, P., Ndiaye, D., Sarr, O., Mboup, S., Marsh, K. Daily, J.P., Tavul, L., Imrie, H., Day, K.P. (2011) A Molecular Epidemiological Study of var Gene Diversity to Characterize the Reservoir of Plasmodium falciparum in Humans in Africa. PLoS ONE 6(2) e16629
10. BARRY AE, Trieu A, Fowkes FJ, Pablo J, Kalantari-Dehaghi M, Jasinskas A, Tan X, Kayala MA, Tavul L, Siba PM, Day KP, Baldi P, Felgner PL, Doolan DL. (2011) The stability and complexity of antibody responses to the major surface antigen of Plasmodium falciparum are associated with age in a malaria endemic area. Mol Cell Proteomics. 2011 Aug 8. [Epub ahead of print] PMID: 21825279

Current Laboratory Members

Faculty Member: Alyssa Barry, BSc(Hons) Tas PhD Melb

Postdoctoral Fellow: Gabrielle (Abby) Harrison, BSc MSc Massey (NZ), DPhil Oxford (UK)

Postdoctoral Fellow: Stephanie Monk, BSc(Hons) York (UK), MSc PhD Edinburgh (UK)

Honourary Postdoctoral Fellow: Alicia Arnott, BMedSci(Hons) Deakin

PhD student: Charlie Jennison, BSc Leeds, MSc LSHTM

PhD student: Sofonias Kifle, BEd. Jimma (Ethiopia), MSc Addis Ababa (Ethiopia)

Research Assistant: Raksmei Keo, BAppSci RMIT

UROP Student: Sally Higgins