Dr Jody Zawadzki

Position

Senior Research Scientist, post-doctoral fellow

Address

Department of Primary Industries, Victoria
475 Mickleham Rd,
Attwood, 3049, Victoria, Australia
T   + 61 (03) 9217 4200
F   + 61 (03) 9217 4299
E   Jody.Zawadzki@dpi.vic.gov.au

Research interests

The discovery of novel targets for the immunological control of sheep nematode parasites that are of economic importance to the Australian agricultural industry. Specific projects involve:

• The development of in vitro culture methods for parasitic nematodes.
• The identification of cell surface and secretory/excretory molecules.
• The development of RNA interference for target validation.
• The production of recombinant proteins.

Qualifications

PhD, '03

Selected Publications

Zawadzki JL., Presidente PJA. Meeusen EN and De Veer MJ (2006). RNAi in Haemonchus contortus: a potential method for target validation. Trends in Parasitology, 22, 495-499.

Mullin KA, Foth BJ, Ilgoutz SC, Callaghan JM, Zawadzki JL, McFadden GI, McConville MJ. (2001). Regulated degradation of an endoplasmic reticulum membrane protein in a tubular lysosome in Leishmania mexicana. Mol Biol Cell. 12, 2364-2377.

Hilley JD, Zawadzki JL, McConville MJ, Coombs GH, Mottram JC. (2000). Leishmania mexicana mutants lacking glycosylphosphatidylinositol (GPI):protein transamidase provide insights into the biosynthesis and functions of GPI-anchored proteins. Mol Biol Cell. 11, 1183-1195.

Ilgoutz SC, Zawadzki JL, Ralton JE, McConville MJ. (1999). Evidence that free GPI glycolipids are essential for growth of Leishmania mexicana. EMBO J. 18, 2746-55.

Moss JM, Reid GE, Mullin KA, Zawadzki JL, Simpson RJ, McConville MJ. (1999). Characterization of a novel GDP-mannose:Serine-protein mannose-1-phosphotransferase from Leishmania mexicana. J Biol Chem. 274, 6678-6688.

Zawadzki J, Scholz C, Currie G, Coombs GH, McConville MJ. (1998). The glycoinositolphospholipids from Leishmania panamensis contain unusual glycan and lipid moieties. J Mol Biol. 282, 287-299.