Professor Marshall Lightowlers
Position
Professor
Principal Research Fellow, NHMRC
Address
The University of Melbourne
Faculty of Veterinary Science
250 Princes Highway,
Werribee, Victoria 3030 Australia
Email: marshall@unimelb.edu.au
http://research.vet.unimelb.edu.au/staff.php?staffID=324
Research interests
Vaccination, cestodes, hydatid disease, cysticercosis
Qualifications
BSc(Hons), PhD
Ten Most Significant Publications
Johnson, K.S., Harrison, G.B.L., Lightowlers, M.W., O'Hoy, K.L., Dempster, R.P., Lawrence, S.B., Vinton, J.G., Heath, D.D. and Rickard, M.D. 1989. Vaccination against ovine cysticercosis using a defined recombinant antigen. Nature, 338:585-587. Role 2.
Lightowlers, M.W., Liu, D., Haralambous, A. and Rickard, M.D. 1989. Subunit composition and specificity of the major cyst fluid antigens of Echinococcus granulosus. Molecular and Biochemical Parasitology, 37:171-182.
Lightowlers, M.W., Rolfe R. and Gauci, C.G. 1996. Taenia saginata: Vaccination against cysticercosis in cattle with recombinant oncosphere antigens. Experimental Parasitology, 84:330-338.
Lightowlers, M.W., Waterkeyn, J.G., Rothel, J.S., Gauci, C.G, Cowman, A.F. and Harrison, G.B.L. 1996. Host-protective fragments and antibody binding epitopes of the Taenia ovis 45W recombinant antigen, Parasite Immunology, 18: 507-513. Role 1.
Lightowlers, M.W., Lawrence, S.B., Gauci, C., Young, J., Ralston, M., Maas, D. and Heath, D.D. 1996. Vaccination against hydatidosis using a defined recombinant antigen. Parasite Immunology, 18:457-462.
Woollard, D.J., Gauci, C.G., Heath, D.D. & Lightowlers, M.W. 2001. Protection against hydatid disease induced with the EG95 vaccine is associated with conformational determinates. Vaccine 19: 498-507.
Gauci, C. & Lightowlers, M.W. 2003. Molecular cloning of genes encoding oncosphere proteins reveals conservation of modular protein structure in cestode antigens. Molecular and Biochemical Parasitology 127: 193-198.
Flisser, A., Gauci, C.G., Zoli, A., Martinez-Ocana, J., Garza-Rodriguez, A., Dominguez-Alpizar, J.L., Maravilla, P., Rodriguez-Canul, R., Avila, G., Aguilar-Vega, L., Kyngdon, C., Geerts, S. & Lightowlers, M.W. 2004. Induction of protection against porcine cysticercosis by vaccination with recombinant oncosphere antigens. Infection and Immunity 72: 5292-5297.
Gonzalez, A. E., Gauci, C.G., Barber, D., Gilman, R.H., Tsang, V.C.W., Garcia, H.H., Verastegui, M. & Lightowlers, M.W. 2005. Vaccination of pigs to control human neurocysticercosis. American Journal of Tropical Medicine and Hygiene, 72: 837-839 Role 2.
Gauci, C., Vural, G., Oncel, T., Varcasia, A., Damian, V., Kyngdon, C.T., Craig, P.S., Anderson, G.A. and Lightowlers, M.W. 2007. Vaccination with recombinant oncosphere antigens reduces the susceptibility of sheep to infection with Taenia multiceps. International Journal fort Parasitology, in press.
Currently Held Grants
2005-2009; NHMRC "Immunological prevention of hydatid disease and cysticercosis" Project 350279. M. Lightowlers
2006-2010; NHMRC Fellowship 400109 M. Lightowlers
2005-2009; Welcome Trust "Optimisation and field testing of a practical vaccine against Taenia solium cysticercosis in pigs" Research grant GR075818MA M. Lightowlers, A. Gonzalez, A. Zoli, A. Flisser
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